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Curing blindness with stem cells

StemSight cures severe corneal blindness with an off-the-shelf stem cell therapy.
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European Healthtech Investment Forum 2022

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Tech Tour's flagship event for Europe's most innovative companies

"The most innovative startup in health and life sciences in Europe"

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BioFIT 2020

 

Corneal blindness is a global problem

Over 12 million people suffer from corneal blindness worldwide, as there is a huge shortage of corneal tissue transplants. Our aim is to make spare parts for the cornea that don't rely on donor tissue. 

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StemSight's founding team have worked with novel biomaterial solutions for ophthalmic applications and culture and differentiation methods for human induced pluripotent stem cells (hiPSC) for several years. Building on this experience, StemSight is developing new cell therapy products for the treatment of blindness.

StemSight's first target indication is limbal stem cell deficiency (LSCD), a severe rare disease of the cornea currently without valid treatment options for patients suffering from LSCD in both eyes. StemSight's off-the-shelf stem cell product could provide these patients with a cure to regain their vision.

 

In the future, we aim to use the same stem cells to make other types of corneal cells, so that we can help patients suffering from other forms of blindness, such as corneal endothelial dystrophies.

Pioneering solutions to cure blindness

StemSight develops cell-based therapies to treat corneal blindness using allogeneic induced pluripotent stem cells (iPSCs).

Limbal stem cells

Often caused by burns or chemical injuries to the surface of the eye, limbal stem cell deficiency (LSCD) results in overgrowth of surrounding tissue and blood vessels to the surface of the eye. This painful and blinding condition goes often untreated due to poor long-term outcomes of existing solutions. We aim to permanently restore vision to patients with LSCD by delivering new limbal stem cells with real regeneration potential.

Corneal endothelial cells

Corneal endothelial dysfunction is the underlying cause in about 40 % of all corneal transplantations done today. With the overwhelming shortage of donor cornea tissue, we propose a method independent of any donor material for the production of corneal endothelial cells. StemSight's endothelial cells on top of a carrier material can be used similarly to DSAEK endothelium transplantation.

 
 

Our team

The team compliments the scientific excellence in stem cells and tissue engineering of the founder team with experience from clinical ophthalmology and pharma industry in their board of directors.

Laura Koivusalo
CEO

DSc, Stem cells

and tissue engineering

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Anni Mörö
COO

PhD, Biomaterials and cellular interactions

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Tanja Ilmarinen
CSO

PhD, Cell biology and ocular in vivo models

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Heli Skottman
CTO

Prof., GMP production of human stem cells

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Aapo Kiviniemi
CLO

Master of Laws, Executive MBA. Corporate agreements and commercialization of research

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Our Board and Advisors consists of business professionals, clinicians, regulatory experts and medical advisors.

 

News and Events

28/03/2022

StemSight winner of two Tech Tour events

StemSight was selected among the best presenting companies in two consecutive events organized by Tech Tour. The European Healthtech Investment Forum and the Future22 flagship event for the very best innovative companies.

15/02/2022

Heli Skottman a finalist for Innovation Professor of the year

Business Finland, Spinverse and Technology Industry Finland have selected our CTO and founder Heli as one of the three finalists for the 2nd Innovation Professor of the Year award. We're very proud of her!

23/10/2021

Laura Koivusalo awarded by JCI Finland 

StemSight's CEO Laura was awarded as one of Finland's Ten Outstanding Young Persons (TOYP) 2021 by JCI Finland. Congratulations!

14/09/2021

StemSight featured in Sifted

Following the press release of StemSight's seed investment, the prime European startup media Shifted did a great piece on the future of stem cell therapies to cure blindness, by interviewing our CEO Laura.

15/03/2022

StemSight awarded 50 000 € Silmu grant

StemSight received the 50 000 € Silmu grant from Instrumentarium Science Foundation. The foundation has a long history in supporting research in medical technologies and life science.

13/01/2022

Tissue Cure Alliance Finland seminar on iPSC and regenerative medicine

StemSight - as part of Tissue Cure Alliance Finland - participates in the free seminar on iPSCs and regenerative medicine on Jan 20 2022. Sign up to hear and discuss the topic with the experts!

11/10/2021

StemSight in Slush100 pitching competition

StemSight was selected among the top 100 early-stage startups to prequalify for the Slush100 pitching competition. The finale on the big stage in Slush 2021 only has room for 3 of the best pitching companies, will StemSight be among them?

14/09/2021

StemSight closes 500 k€ seed round

We are proud to announce the successful seed funding round lead by Finnish deep-tech VC Voima Ventures and Avohoidon tutkimussäätiö. This funding goes to further development of StemSight's cell therapy product for limbal stem cell defiency.

 

Meet us at these upcoming events!

Embryonic Stem Cells

BIO EUROPE SPRING

Online

March 28-30

Scientist on Computer

Venture Summit Digital Connect

Online

March 29-31

Pipetting Samples

Advanced Therapies 

London, UK

May 24-25

Interested to hear about our most recent updates, upcoming milestones and investment opportunities? Have an potential collaboration idea? Just thought of someone we absolutely need to meet to help us along?

 

Send us a message!